Dr Bibi Marjan Razavi

Assistant Professor of Toxicology

Address: Department of Pharmacodynamy and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.

Tel: (+98)-511- 8823255(326)

Fax: (+98)-511- 8823251

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Updated at:                           

                                                       und Educational Background 

Professional Doctorate in Pharmacy (Pharm.D) 1992-1997

School of Pharmacy, Mashhad University of Medical Science, Mashhad, Iran.

Doctorate of Philosophy, Toxicology 2007-2012

School of Pharmacy, Mashhad University of Medical Science, Mashhad, Iran.

                                                                   Research Interests

Cellular and molecular toxicology

Cardiovascular toxicology

Neurobehavioral pharmacology

                                                                       Publications

1-      Razavi-Azarkhiavi, K., Jafarian, A.H., Abnous, K., Razavi, B.M., Shirani, K., Zeinali, M., Jaafari, M.R., Karimi, G. The Comparison of Biodistribution, Efficacy and Toxicity of Two PEGylated Liposomal Doxorubicin Formulations in Mice Bearing C - 26 Colon Carcinoma: A Preclinical Study. Drug research 2016, 66: 330-336.(IF: 0.7)

2-     Javidi S, Razavi BM, Hosseinzadeh H. A review of Neuropharmacology Effects of Nigella sativa and Its Main Component, Thymoquinone. Phytotherapy Research 2016, Article in press (IF:  2.66)

3-      Yazdian-robati R, Pourtaji, A., Rashedinia, M., Hosseinzadeh, H., Ghorbani, M., Razavi, B.M., Ramezani, M., Abnous, K. Screening and identification of SUMP-proteins in sub-acute treatment with diazinon. Iranian Journal of Basic Medical Sciences 2015, 18: 1240-1244 (IF:1.228)

4-      Razavi BM, Hosseinzadeh H. Saffron as an antidote or a protective agent against natural or chemical toxicities. DARU Journal of Pharmaceutical Sciences 2015, 23:31(IF:1.64).

5-      Somaye Ardebili Dorri , Hossein Hosseinzadeh,Khalil Abnous, Faezeh Vahdati Hasani, Rezvan Yazdian Robati, Bibi Marjan Razavi. Involvement of BDNF neurotrophic factor on malathion induced depressive like behavior in subacute exposure and protective effects of crocin. Iranian Journal of Basic Medical sciences. Article In Press (IF: 1.228).

6-      Farzaneh Zolfagharian, Bibi Marjan Razavi, Hossein Hosseinzadeh.Anticonvulsant Effect of Satureja hortensis L. Aerial Parts Extracts in Mice. Avicenna journal of Phytomedicine. Article In Press.

7-      Razavi BM, Hosseinzadeh H, Abnous K, Khoei  A , Imenshahidi M.  Protective effect of crocin on diazinon induced apoptosis in vascular system in subchronic exposure. Toxicology and Industrial Health. 2014, doi: 10.1177/0748233714554941 (IF:1.85).

8-      Razavi  BM, Arasteh E, Imenshahidi  M, Iranshahi M. Antihypertensive effect of auraptene, a monoterpene coumarin from the genus Citrus, upon chronic administration. Iranian Journal of Basic Medical sciences. 2015, 18(2):153-8 (IF: 1.228).

9-      Soghra Mehri, Mehran Shahi, Bibi Marjan Razavi, Faezeh Vahdati Hassani, Hossein Hosseinzadeh. ^.Neuroprotective effect of thymoquinone in acrylamide-induced neurotoxicity in Wistar rats. Iranian Journal of Basic Medical sciences. 2014, 17: 1007–1011 (IF: 1.228).

10-  Elahe Esmaeelpanah; Alireza Rahmatkhah; Narges Poormahmood,  Bibi Marjan Razavi; FaezehVahdati Hasani; Hossein Hosseinzadeh. Protective Effect of Green Tea Aqueous Extract on Acrylamide Induced Neurotoxicity. Jundishapur Journal of Natural Pharmaceutical Products.  2015 , 10(2): e18406.

11-  Imenshahidi, M., Razavi, B.M., Faal, A., Gholampoor, A., Mousavi, S.M., Hosseinzadeh, H.  The Effect of Chronic Administration of Safranal on Systolic Blood Pressure in Rats. Iranian Journal of Pharmaceutical Research. 2015, 14 (2). (IF: 1.06).

12-  Behravan E, Razavi BM, Hosseinzadeh H. Review of plants and their constituents in the therapy of cerebral ischemia. Phytother Res. 2014 28(9):1265-74. doi: 10.1002/ptr.5187. (IF: 2.66).

13-  Razavi BM, Hosseinzadeh H, Abnous K, Imenshahidi M. Protective effect of crocin on diazinon induced vascular toxicity in subchronic exposure in rat aorta ex-vivo. Drug Chem Toxicol. 2014, 37(4):378-83.

14-  Razavi BM, Hosseinzadeh H. A review of the effects of Nigella sativa L. and its constituent, thymoquinone, in metabolic syndrome. J Endocrinol Invest. 2014 , 37: 1031-40. (IF:1.55)

15-  Razavi BM, Hosseinzadeh H, Imenshahidi M, Malekian M, Ramezani M, Abnous K. Evaluation of Protein Ubiquitylation in Heart Tissue of Rats Exposed to Diazinon (an Organophosphate Insecticide) and Crocin (an Active Saffron Ingredient): Role of HIF-1α. Drug Res. 2014 Nov 4. [Epub ahead of print]. (IF:0.7)

16-  Speer T, Owala FO, Holy EW, Zewinger S, Frenzel FL, Stähli BE, Razavi M, Triem S, Cvija H, Rohrer L, Seiler S, Heine GH, Jankowski V, Jankowski J, Camici GG, Akhmedov A, Fliser D, Lüscher TF, Tanner FC. Carbamylated low-density lipoprotein induces endothelial dysfunction. Eur Heart J. 2014 14;35(43) . (IF:15.2)

17-  Marzieh R, Hosseinzadeh H, Mohsen I, Parisa L, Bibi Marjan R, Khalil A. Effect of exposure to diazinon on adult rat's brain. Toxicol Ind Health. 2013 Nov 11. [Epub ahead of print] . (IF:1.85)

18-  Vahdati Hassani, F., Naseri, V., Razavi, B.M., Mehri, S., Abnous, K., Hosseinzadeh, H. Antidepressant effects of crocin and its effects on transcript and protein levels of CREB, BDNF, and VGF in rat hippocampus . DARU, Journal of Pharmaceutical Sciences. 2014, 22 (1). (IF:1.64 )

19-  Ghasemi, T., Abnous, K., Vahdati, F., Mehri, S., Razavi, B.M., Hosseinzadeh, H. Antidepressant Effect of Crocus sativus Aqueous Extract and its Effect on CREB, BDNF, and VGF Transcript and Protein Levels in Rat Hippocampus. Drug Research. 2015, 65; 337-43. (IF:0.7)

20-  Ziaee, T., Razavi, B.M., Hosseinzadeh, H.Saffron Reduced Toxic Effects of its Constituent, Safranal, in Acute and Subacute Toxicities in Rats . Jundishapur Journal of Natural Pharmaceutical Products. 2014,  9 (1), pp. 3-8. 

21-  Imenshahidi, M., Razavi, B.M., Faal, A., Gholampoor, A., Mousavi, S.M., Hosseinzadeh, H. Effects of chronic crocin treatment on desoxycorticosterone acetate (doca)-salt hypertensive rats Iranian Journal of Basic Medical Sciences. 2014, 17 (1), pp. 9-13. (IF: 1.228)

22-  Imenshahidi, M., Razavi, B.M., Faal, A., Gholampoor, A., Mousavi, S.M., Hosseinzadeh, H. The effect of chronic administration of saffron (Crocus sativus) stigma aqueous extract on systolic blood pressure in rats. Jundishapur Journal of Natural Pharmaceutical Products. 2013, 8 (4), pp. 175-179. 

23-  Razavi BM, Hosseinzadeh H, Movassaghi AR, Imenshahidi M, Abnous KH. Protective effect of crocin on diazinon induced cardiotoxicity in subcronic exposure. Chemico- biological interactions. 2013; 25: 547-55. (IF: 2.967)

24-  Lari P, Abnous K, Imenshahidi M, Rashedinia M, Razavi M, Hosseinzadeh H. Evaluation of diazinon-induced hepatotoxicity and protective effects of crocin.Toxicology and Industrial Health.2013. (IF: 1.85)

25-  Moallem SA, Afshar M, Etemad L, Razavi BM, Hosseinzadeh H. Evaluation of teratogenic effects of crocin and safranal, active ingredients of saffron, in mice. Toxicol Ind Health. 2013 Oct 4. [Epub ahead of print] (IF:1.85)

26-  Razavi M, Hosseinzadeh H, Abnous  Kh, Motamedshariaty VS , Imenshahidi M. Crocin restores hypotensive effect of subchronic administration of diazinon in rats. Iranian Journal of Basic Medical Sciences. 2013, 16, 64-72. (IF: 1.228)

27-  Hosseinzadeh H, ImenshahidiM, Hosseini M, Razavi M.Effect of Linalool on Morphine Tolerance and Dependence in Mice. Phytotherapy research, FEB 2012 (IF: 2.66)

28-  Karimi G, Aghasizadeh M, Razavi M, Taghiabadi E.  Protective effects of aqueous and ethanolic extracts of Nigella sativa L. and Portulaca oleracea L. on free radical induced hemolysis of RBCs.  DARU, 19, November 2011 (IF:1.62)

29-  Behravan J, Mosafa F, Soudmand N, Taghiabadi E, Razavi M, Karimi G. Protective effects of aqueous and ethanolic extracts of Portulaca oleracea L. aerial parts on H2O2-induced DNA damage in lymphocytes by comet assay. Journal of Acupuncture and Meridian studies. September 2011, PP. 193–197

30-  Karimi G, Hosseinzadeh H, Rassoulzadeh M, Razavi M, Taghiabadi E. Antinociceptive effect of Elaeagnus angustifolia fruits in sciatic nerve ligated mice. Iranian Journal of Basic Medical Sciences . 2009. (IF:1.228)

31-  Karimi G, khoei A,  Babaei J, Taghiabadi E, Razavi M. Protective effect of aqueous and ethanolic extracts of Portulaca Oleracea against cisplatin induced nephrotoxicity. Iranian Journal of Basic Medical Sciences. 2009; PP. 31-35. (IF:1.228)

32-  Hosseinzadeh H, Sayadi M, Taghiabadi E, Razavi M^. Anticonvulsant  effect of Citrus  Bigaradia  Duh. Leaves extracts in mice. Pharmacologyonline. 2009; PP.412-418.

33-  Hosseinzadeh H, Fadishei M,Razavi M, Taghiabadi E. Circadian variation of antinociceptive effect of adenosine and adenosine A1 receptor agonists, N6-phenylisopropyl adenosine and 2-chloroadenosine, in mice. Pharmacologyonline. 2009;539-543.

34-  Hosseinzadeh H, Mirshojaeian M, Razavi, M. Antiemetic effect of Pistacia Vera L. (Pistachio) leaves and nuts aqueous extracts in young chickens. Pharmacologyonline, 2008; 568-571.