Dr Zhila Taherzadeh

Assistant Professor of clinical pharmacology/ physiology

        [at]mums.ac.ir
[at]yahoo.com

• Address: Targeted drug delivery  Research Center, Neurogenic Inflammation Research Center, Department of Pharmacodynamy and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

Tel: +98 5138823255

Fax+98 5138823251

This email address is being protected from spambots. You need JavaScript enabled to view it.

……….[at]yahoo.com

Updated at:                           

                                                       und Educational Background 

Pharm.D. (Doctor of Pharmacy)

1991-1996              School of Pharmacy, Mashhad University of  Medical       Sciences, Mashhad, IRAN        

  Ph.D.

  2005-2011             Academic Medical Center, Dept. of Biomedical  Engineering & Physics and Dept. Internal Medicine, Amsterdam, The Netherlands

Thesis title: “Hypertension and Resistance Vessel Function and Structure: Role of Ethnicity and Inflammation”

                                                                   Research Interests

• Clinical Research on Traditional Plant Medicines (EFFICACY AND SAFETY)
• Inflammation and immune system polarization
• Educational research
• Hypertension and Resistance Vessel Function and Structure

                                                                       Publications

1. Taherzadeh, Z.,  Karamat, F.A. ,  Ankum, W.M.,  Clark, J.F.,  Van Montfrans, G.A.,  Van Bavel, E.,  Brewster, L.M. The Effect of Creatine Kinase Inhibition on Contractile Properties of Human Resistance Arteries. American Journal of Hypertension. 2016 Feb; 29(2): 170-177

1. Nabovati, E.,  Vakili-Arki, H.,  Taherzadeh, Z.,  Saberi, M.R.,  Abu-Hanna, A.,  Eslami, S. Incidence rate and pattern of clinically relevant potential drug-drug interactions in a large outpatient population of a developing country. Research in Pharmaceutical Sciences. 2016; 11(3): 219-226

1. Sarbaz M, Kimiafar K, Sheikhtaheri A, Taherzadeh Z, Eslami S. Nurses' Information Seeking Behavior for Clinical Practice: A Case Study in a Developing Country. Stud Health Technol Inform. 2016;225:23-7.

1. Nabovati E, Vakili-Arki H, Taherzadeh Z, Hasibian MR, Abu-Hanna A, Eslami S. Drug-drug interactions in inpatient and outpatient settings in Iran: a systematic review of the literature. Daru. 2014 Jun 25;22:52. doi: 10.1186/2008-2231-22-52. Review

1. Medlock S, Eslami S, Askari M, Taherzadeh Z, Opondo D, de Rooij SE, Abu-Hanna A.

Co-Prescription of Gastroprotective Agents and Their Efficacy in Elderly Patients Taking Non-  Steroidal Anti-Inflammatory Drugs: a Systematic Review of Observational Studies. Clin Gastroenterol Hepatol. 2013 Jun 20. doi:pii: S1542-3565(13)00803-3.

1. Eslami S, Taherzadeh Z, Schultz MJ, Abu-Hanna A. Glucose variability measures and their effect on mortality – A systematic review. Intensive Care Med. 2011 Apr;37(4):583-93.

1. Taherzadeh Z, Brewster LM, van Montfrans GA, VanBavel E. Function and structure of resistance vessels in black and white people. J Clin Hypertens. 2010; 12:431-8.

1. Brewster LM, Taherzadeh Z, Volger S, Clark JF, Rolf T, Wolf H, Vanbavel E, van Montfrans GA. Ethnic differences in resistance artery contractility of normotensive pregnant women. Am J Physiol Heart Circ Physiol. 2010; 299:H431-6.

1. Taherzadeh Z, VanBavel E, de Vos J, Matlung HL, van Montfrans G, Brewster LM, Seghers L, Quax PH, Bakker EN. Strain-dependent susceptibility for hypertension in mice resides in the natural killer gene complex. Am J Physiol Heart Circ Physiol. 2010; 298:H1273-82.

1. Z. Taherzadeh, E. VanBavel, G.A. van Montfrans, C.E. van der Zee, F. Streijger and L.M. Brewster. Structure and function of resistance vessels from BB-creatine kinase and ubiquitous Mi-CK knockout mice.

                                                                      Presentations

1. Pharmacotherapy considerations in elderly. International congress of quality, safety and rational use of drugs, Mashhad, Iran, 2015
2. Structure and function of resistance vessels from BB-Creatine kinase and ubiquitous Mi-CK knockout mice. Iranian pharmaceutical sciences congress(IPSC), Tehran, 2015
3. The Effect of Creatine Kinase Inhibition on Contractile Properties of Human Resistance Arteries. 1^st International and 22^nd Iranian congress of physiology and pharmacology, Kashan, 2015
4. Contractility of isolated resistance artery in normotensive women with uterine leiomyomata, European Society of Hypertension, Oslo, Norway, 2010
5. Strain-dependent susceptibility for hypertension in mice resides in the natural killer gene complex, Florida, USA, 2009
6. Development of hypertension and vascular remodeling depend on the immunological background in mice, European Society of Hypertension, Milan, Italy, 2009
7. Hypertension and vascular remodeling depend on the immunological background in mice, European Society of Hypertension, Berlin, Germany, 2008
8. Strain-dependent hypertension and vascular remodeling, a key role for leukocyte activation, Microcirculatie en Vasculaire Biologie, Mastricht, The Netherlands, 2008
9. Strain-dependent hypertension and vascular remodeling, a key role for leukocyte activation, Netherlands Society of Hypertension, Utrecht, The Netherlands, 2007
10. Vascular Contractility in Resistance Arteries from BB and Mi-Creatine Kinase Knockout Mice, European Meeting on Hypertension, Milan, Italy, 2007
11. Vascular Contractility in Resistance Arteries from BB and Mi-Creatine Kinase Knockout Mice, 24th European Conference on Microcirculation, Amsterdam, The Netherlands, 2006
12. Simulator software for prescription reading in pharmacies, 8th Iranian Pharmaceutical Sciences Seminar, Shiraz, Iran, 2002
13. Multimedia searcher for pharmaceutical and toxic agents in Iran, 6th Iranian Toxicology and Drug Poisoning Congress, Ahvaz, Iran, 1999
14. Multimedia database of drug information in Iranian formulary, 5th Iranian Pharm.D. Student Seminar, Tehran, Iran, 1999
15. Education Technology in Iran, 5th Iranian Pharm.D. Student Seminar, Tehran, Iran,1999
16. Antimicrobial activity of Iranian plant (Khorasan province), 3th Iranian Pharm.D. Student Seminar, Tehran, Iran, 1996
17. Library management software, 2th Iranian Phrm.D. Student Seminar, Mashhad, Iran, 1995
18.  Physical pharmacy parameters calculator, 2th Iranian Phrm.D. Student Seminar, Mashhad, Iran, 1995
19. Elements Table Software, 1th Iranian Pharm.D. Student Seminar, Tabriz, Iran, 1994

Design of Iranian plant systematic poster, 1th Iranian Pharm.D. Student Seminar, Tabriz, Iran, 1994

                                                                    Honors & Awards

Honor researcher student, 2th Iranian Pharm.D. Students Seminar, Mashhad, Iran, 1995

Members                                                  hip Membership

Assistant Professor of Targeted drug delivery  Research Center

Assistant Professor of Neurogenic Inflammation Research Center

Food Analysis Laboratory Control Center; Vice - Chancellor for Food and Drug, 2000-2002

                                                           Administrative Responsibilities

v  Director of Office Talented, School of Pharmacy, Mashhad University of Medical Sciences.

v  Responsible Pharmacist at 22^nd Bahman Pharmacy, affiliated to Mashhad University of Medical Sciences

Courses & Workshops

Scientific writing for publishing in peer-reviewed medical journals. Tehran, Iran, January 2016

Health economics academy, Tehran, Iran, September 2015

Practical Biostatistics, Amsterdam, The Netherlands, Jan 10-Feb 14, 2006

Expert management of medical literature, Amsterdam, The Netherlands, 2006

Oral presentation in English, Amsterdam, The Netherlands, 2006 2e Cardiovascular Research Institute Amsterdam (CRIA)

basic-course (Vascular Biology), Papendal, The Netherlands, 2005

Other Skills

DrSeyed Mohammad Taghdisi Heidarian

Assistant Professor of Pharmaceutical Biotechnology

        [at]mums.ac.ir
[at]yahoo.com

Address: Targeted Drug Delivery Research Center

Department of Pharmaceutical Biotechnology

School of pharmacy, Mashhad University of Medical Sciences

Mashhad, IRAN

Tel: (051) 38813255

Fax(051) 38813251

taghdisihm@mums.ac.ir

This email address is being protected from spambots. You need JavaScript enabled to view it.

Updated at:                           

                                                       und Educational Background 

1. School of pharmacy, Mazandaran University of Medical Sciences, Sari, Iran

          Pharm D supervisor: Dr. Hosseinimehr, Dr. Emami

          Research Field: Bioorganic and Medicinal Chemistry

          Pharm D thesis: Synthesis of 5,7-Dihydroxychromone-2-carboxylic acid

1. Department of Pharmaceutical Biotechnology, Mashhad University of Medical Sciences,          Mashhad, Iran

          PhD supervisor: Dr Abnous and Dr. Behravan

          Research Field: Targeted delivery, Aptamer and Biotechnology

          PhD thesis: Generation of aptamers for MCF-7 cells and using them for targeted delivery 

           of siRNA to breast cancers  

1. Ph.D Sabbatical: University of Bonn, Germany, 2011 (8 months)

Supervisor: Prof. Mayer

                                                                   Research Interests

Aptamers, Aptasensors (electrochemical, colorimetric and fluorescent aptasensors), Cell-SELEX, SELEX, Targeted drug delivery

                                                                       Publications

Raeisossadati MJ, Danesh NM, Borna F, Gholamzad M, Ramezani M, Abnous K, Taghdisi SM. Lateral flow based immunobiosensors for detection of food contaminants. Biosensors and Bioelectronics. 2016. (IF=7.47)

2.         Yazdian-Robati R, Ramezani M, Jalalian SH, Abnous K, Taghdisi SM. Targeted Delivery of Epirubicin to Cancer Cells by Polyvalent Aptamer System in vitro and in vivo. Pharmaceutical Research. 2016:1-9. (IF=3.26)

3.         Nameghi MA, Danesh NM, Ramezani M, Hassani FV, Abnous K, Taghdisi SM. A fluorescent aptasensor based on a DNA pyramid nanostructure for ultrasensitive detection of ochratoxin A. Anal Bioanal Chem. 2016. Epub 2016/06/18. (IF=3.12)

4.         Taghdisi SM, Danesh NM, Ramezani M, Abnous K. A novel M-shape electrochemical aptasensor for ultrasensitive detection of tetracyclines. Biosensors and Bioelectronics. 2016;85:509-14. (IF=7.47)

5.         Abnous K, Danesh NM, Ramezani M, Taghdisi SM, Emrani AS. A novel electrochemical aptasensor based on H-shape structure of aptamer-complimentary strands conjugate for ultrasensitive detection of cocaine. Sensors and Actuators, B: Chemical. 2016;224:351-5. (IF=4.75)

6.         Abnous K, Danesh NM, Sarreshtehdar Emrani A, Ramezani M, Taghdisi SM. A novel fluorescent aptasensor based on silica nanoparticles, PicoGreen and exonuclease III as a signal amplification method for ultrasensitive detection of myoglobin. Analytica Chimica Acta. 2016;917:71-8. (IF=4.71)

7.         Danesh NM, Ramezani M, Emrani AS, Abnous K, Taghdisi SM. A novel electrochemical aptasensor based on arch-shape structure of aptamer-complimentary strand conjugate and exonuclease I for sensitive detection of streptomycin. Biosensors and Bioelectronics. 2016;75:123-8. (IF=7.47)

8.         Emrani AS, Danesh NM, Lavaee P, Ramezani M, Abnous K, Taghdisi SM. Colorimetric and fluorescence quenching aptasensors for detection of streptomycin in blood serum and milk based on double-stranded DNA and gold nanoparticles. Food Chemistry. 2016;190:115-21. (IF=4)

9.         Emrani AS, Danesh NM, Ramezani M, Taghdisi SM, Abnous K. A novel fluorescent aptasensor based on hairpin structure of complementary strand of aptamer and nanoparticles as a signal amplification approach for ultrasensitive detection of cocaine. Biosensors and Bioelectronics. 2016;79:288-93. (IF=7.47)

10.       Hashemzaei M, Karami SP, Delaramifar A, Sheidary A, Tabrizian K, Rezaee R, Taghdisi SM. Anticancer effects of co-administration of daunorubicin and resveratrol in MOLT-4, U266 B1 and Raji cell lines. Farmacia. 2016;64(1):36-42. (IF=1.16)

11.       Khansarizadeh M, Mokhtarzadeh A, Rashedinia M, Taghdisi SM, Lari P, Abnous KH, et al. Identification of possible cytotoxicity mechanism of polyethylenimine by proteomics analysis. Human and Experimental Toxicology. 2016;35(4):377-87. (IF=1.6)

12.       Moghadam M, Sankian M, Abnous K, Varasteh A, Taghdisi SM, Mahmoudi M, et al. Cell-SELEX-based selection and characterization of a G-quadruplex DNA aptamer against mouse dendritic cells. International Immunopharmacology. 2016;36:324-32. (IF=2.55)

13.       Ramezani M, Danesh NM, Lavaee P, Abnous K, Taghdisi SM. A selective and sensitive fluorescent aptasensor for detection of kanamycin based on catalytic recycling activity of exonuclease III and gold nanoparticles. Sensors and Actuators, B: Chemical. 2016;222:1-7. (IF=4.75)

14.       Robati RY, Arab A, Ramezani M, Langroodi FA, Abnous K, Taghdisi SM. Aptasensors for quantitative detection of kanamycin. Biosensors and Bioelectronics. 2016;82:162-72. (IF=7.47)

15.       Soheili V, Taghdisi SM, Hassanzadeh Khayyat M, Fazly Bazzaz BBS, Ramezani M, Abnous K. Colorimetric and ratiometric aggregation assay for streptomycin using gold nanoparticles and a new and highly specific aptamer. Microchimica Acta. 2016;183(5):1687-97. (IF=4.83)

16.       Taghdisi SM, Danesh NM, Beheshti HR, Ramezani M, Abnous K. A novel fluorescent aptasensor based on gold and silica nanoparticles for the ultrasensitive detection of ochratoxin A. Nanoscale. 2016;8(6):3439-46. (IF=7.76)

17.       Taghdisi SM, Danesh NM, Lavaee P, Emrani AS, Hassanabad KY, Ramezani M, et al. Double targeting, controlled release and reversible delivery of daunorubicin to cancer cells by polyvalent aptamers-modified gold nanoparticles. Materials Science and Engineering C. 2016;61:753-61. (IF=3.42)

18.       Taghdisi SM, Danesh NM, Lavaee P, Ramezani M, Abnous K. An electrochemical aptasensor based on gold nanoparticles, thionine and hairpin structure of complementary strand of aptamer for ultrasensitive detection of lead. Sensors and Actuators, B: Chemical. 2016;234:462-9. (IF=4.75)

19.       Taghdisi SM, Danesh NM, Nameghi MA, Ramezani M, Abnous K. A label-free fluorescent aptasensor for selective and sensitive detection of streptomycin in milk and blood serum. Food Chemistry. 2016;203:145-9. (IF=4)

20.       Taghdisi SM, Danesh NM, Ramezani M, Abnous K. Targeted delivery of vincristine to T-cell acute lymphoblastic leukemia cells using an aptamer-modified albumin conjugate. RSC Advances. 2016;6(52):46366-71. (IF=3.28)

21.       Taghdisi SM, Danesh NM, Ramezani M, Emrani AS, Abnous K. A novel electrochemical aptasensor based on Y-shape structure of dual-aptamer-complementary strand conjugate for ultrasensitive detection of myoglobin. Biosensors and Bioelectronics. 2016;80:532-7. (IF=7.47)

22.       Taghdisi SM, Danesh NM, Ramezani M, Lavaee P, Jalalian SH, Robati RY, et al. Double targeting and aptamer-assisted controlled release delivery of epirubicin to cancer cells by aptamers-based dendrimer in vitro and in vivo. European Journal of Pharmaceutics and Biopharmaceutics. 2016;102:152-8. (IF=3.97)

23.       Abnous K, Danesh NM, Ramezani M, Emrani AS, Taghdisi SM. A novel colorimetric sandwich aptasensor based on an indirect competitive enzyme-free method for ultrasensitive detection of chloramphenicol. Biosensors and Bioelectronics. 2016;78:80-6. (IF=7.47)

24.       Taghdisi SM, Danesh NM, Lavaee P, Sarreshtehdar Emrani A, Ramezani M, Abnous K. Aptamer Biosensor for Selective and Rapid Determination of Insulin. Analytical Letters. 2015;48(4):672-81. (IF=1.08)

25.       Taghdisi SM, Danesh NM, Lavaee P, Ramezani M, Abnous K. An aptasensor for selective, sensitive and fast detection of lead(II) based on polyethyleneimine and gold nanoparticles. Environmental toxicology and pharmacology. 2015;39(3):1206-11.  (IF=2.18)

26.       Taghdisi SM, Danesh NM, Lavaee P, Emrani AS, Ramezani M, Abnous K. A novel colorimetric triple-helix molecular switch aptasensor based on peroxidase-like activity of gold nanoparticles for ultrasensitive detection of lead(II). RSC Advances. 2015;5(54):43508-14. (IF=3.28)

27.       Taghdisi SM, Danesh NM, Emrani AS, Ramezani M, Abnous K. A novel electrochemical aptasensor based on single-walled carbon nanotubes, gold electrode and complimentary strand of aptamer for ultrasensitive detection of cocaine. Biosensors & bioelectronics. 2015;73:245-50. (IF=7.47)

28.       Sarreshtehdar Emrani A, Danesh NM, Lavaee P, Jalalian SH, Ramezani M, Abnous K, Taghdisi SM. Sensitive and selective detection of digoxin based on fluorescence quenching and colorimetric aptasensors. Analytical Methods. 2015;7(8):3419-24. (IF=1.91)

29.       Ramezani M, Mohammad Danesh N, Lavaee P, Abnous K, Taghdisi SM. A novel colorimetric triple-helix molecular switch aptasensor for ultrasensitive detection of tetracycline. Biosensors and Bioelectronics. 2015;70:181-7. (IF=7.47)

30.       Moosavian SA, Jaafari MR, Taghdisi SM, Mosaffa F, Badiee A, Abnous K. Development of RNA aptamers as molecular probes for HER2+ breast cancer study using cell-SELEX. Iranian Journal of Basic Medical Sciences. 2015;18(6):576-86. (IF=1.2)

31.       Khabbaz LS, Hassanzadeh-Khayyat M, Zaree P, Ramezani M, Abnous K, Taghdisi SM. Detection of kanamycin by using an aptamer-based biosensor using silica nanoparticles. Analytical Methods. 2015;7(20):8611-6. (IF=1.91)

32.       Jalalian SH, Taghdisi SM, Danesh NM, Bakhtiari H, Lavaee P, Ramezani M, et al. Sensitive and fast detection of tetracycline using an aptasensor. Analytical Methods. 2015;7(6):2523-8. (IF=1.91)

33.       Emrani AS, Taghdisi SM, Danesh NM, Jalalian SH, Ramezani M, Abnous K. A novel fluorescent aptasensor for selective and sensitive detection of digoxin based on silica nanoparticles. Analytical Methods. 2015;7(9):3814-8. (IF=1.91)

34.       Danesh NM, Lavaee P, Ramezani M, Abnous K, Taghdisi SM. Targeted and controlled release delivery of daunorubicin to T-cell acute lymphoblastic leukemia by aptamer-modified gold nanoparticles. Int J Pharm. 2015;489:311-7. (IF=3.99)

35.   Taghdisi SM, Schöler KMU, Mayer G. Aptamers and use of the aptamers in the diagnosis and treatment of cancer. European Patent.  03.12.2014. 13169493.7.

36.       Taghdisi SM, Emrani SS, Tabrizian K, Ramezani M, Abnous K, Emrani AS. Ultrasensitive detection of lead (II) based on fluorescent aptamer-functionalized carbon nanotubes. Environmental toxicology and pharmacology. 2014;37(3):1236-42. (IF=2.18)

37.       Taghdisi SM, Danesh NM, Sarreshtehdar Emrani A, Tabrizian K, Zandkarimi M, Ramezani M, et al. Targeted delivery of Epirubicin to cancer cells by PEGylated A10 aptamer. Journal of drug targeting. 2013;21(8):739-44. (IF=2.82)

38.       Jalalian SH, Taghdisi SM, Shahidi Hamedani N, Kalat SA, Lavaee P, Zandkarimi M, et al. Epirubicin loaded super paramagnetic iron oxide nanoparticle-aptamer bioconjugate for combined colon cancer therapy and imaging in vivo. European journal of pharmaceutical sciences. 2013;50(2):191-7. (IF=3.77)

39.       Taghdisi SM, Lavaee P, Ramezani M, Abnous K. Reversible targeting and controlled release delivery of daunorubicin to cancer cells by aptamer-wrapped carbon nanotubes. European journal of pharmaceutics and biopharmaceutics. 2011;77(2):200-6. (IF=3.97)

40.       Entezari Heravi R, Hadizadeh F, Sankian M, Tavakol Afshari J, Taghdisi SM, Jafarian H, et al. Novel selective Cox-2 inhibitors induce apoptosis in Caco-2 colorectal carcinoma cell line. European journal of pharmaceutical sciences. 2011;44(4):479-86. (IF=3.77)

41.       Taghdisi SM, Abnous K, Mosaffa F, Behravan J. Targeted delivery of daunorubicin to T-cell acute lymphoblastic leukemia by aptamer. Journal of drug targeting. 2010;18(4):277-81. (IF=2.82)

42.       Hosseinimehr SJ, Emami S, Taghdisi SM, Akhlaghpoor S. 5,7-Dihydroxychromone-2-carboxylic acid and it's transition-metal (Mn and Zn) chelates as non-thiol radioprotective agents. European journal of medicinal chemistry. 2008;43(3):557-61. (IF=3.9)

43.       Emami S, Hosseinimehr SJ, Taghdisi SM, Akhlaghpoor S. Kojic acid and its manganese and zinc complexes as potential radioprotective agents. Bioorganic & medicinal chemistry letters. 2007;17(1):45-8. (IF=2.48)

                                                                      Presentations

Oral Presentation

1)        Taghdisi SM., et al. Targeted delivery of daunorubicin to T-cell acute lymphoblastic leukemia by aptamer .The First Research Festival of Mashhad University of medical sciences, 2010. 

2)        Taghdisi SM., et al. Reversible Targeting and controlled release delivery of daunorubicin to cancer cells by aptamer-wrapped carbon nanotubes. The Second Research Festival of Mashhad University of medical sciences, 2011. 

3)        Taghdisi SM., et al. Novel broad-spectrum aptamers for tumour cell deprivation .The Third Research Festival of Mashhad University of medical sciences, 2011. 

Poster presentation

1)      Taghdisisi SM., et al. Recent advances in graphene and related material, Singapore 2010.

2)       Taghdisi SM., et al. Specialized festival of position of nano drugs, nano biotechnology, nano biosensors and nano materials in medical sciences, Mashhad, 2009.

   3)  Taghdisi SM., et al. The 13^th Iranian Pharmacy Students seminar, Tabriz, 2007.

    4) Taghdisi SM., et al. The 10^th Iranian Pharmacy Students seminar, Mashhad, 2004.

                                                                    Honors & Awards

1)      Top Ph.D student in the board exam of Mashhad University of Medical Sciences (Pharmaceutical Biotechnology) 2009.

2)      The best lecturer in the Second Research Festival of Mashhad University of Medical sciences, 2011. 

3)      The best lecturer in the Third Research Festival of Mashhad University of Medical Sciences, 2011.  

4)      Top researcher in the Research Festival of Mashhad University of Medical Sciences, 2015.  

Members                                                  hip Membership

                                                           Administrative Responsibilities

Other Skills

Dr Mohsen Tafaghodi (Pharm.D., Ph.D.)

Assistant Professor of pharmaceutics

        [at]mums.ac.ir
[at]yahoo.com

Address: Pharmaceutics and Nanotechnology,

School of Pharmacy,

Nanotechnology Research Center,

Mashhad University of Medical Sciences,

Mashhad-Iran

Tel: ++98-51-38823255-66 (Office)

Fax++98-51-38823251

tafaghodim@mums.ac.ir

Updated at:        June 2016                   

                                                       und Educational Background 

Pharm.D.: School of Pharmacy, Mashhad University of Medical Sciences (1991-1997).

Ph.D. (Pharmaceutics): School of Pharmacy, Mashhad University of Medical Sciences (1997-2003).

Ph.D. thesis title: Nasal immunization using biodegradable microspheres and liposomes: Tetanus toxoid as a model

Research fellowships:

1-      School of Pharmacy, University of Alberta, Canada (cancer vaccination using nano- and microparticulate drug delivery systems).

2-      Leiden/Amsterdam center for Drug Research, University of Leiden, Netherland (preparation and characterization and in vivo study of TMC:HBsAg and chitosan:HBsAg nanoparticles as a nasal delivery /adjuvant system)

                                                                   Research Interests

-          Mucosal and systemic vaccine and drug delivery by nanoparticulate and microparticulate delivery systems (nanospheres, microspheres and liposomes)

                                                                       Publications

1- Diwan, M., Tafaghodi, M., Samuel, J., 2002. Enhancement of immune responses by co-delivery of a CpG oligodeoxynucleotide and tetanus toxoid in biodegradable nanospheres. Journal of Controlled Release, 85, 247-262

2- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R., 2002. Drug delivery from nasal route. Razi,, 155, 32-42.

3- Tafaghodi, M., Hasanzadeh, M., Rahimizadeh, M., 2003. Isolation and identification of Hyoscyamus insanus alkaloids. Iranian journal of Medicinal Plants, 2(7), 29-36.

4- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R.., 2004. Utilization of particulate and immuno-modulating adjuvants for enhancement of immune responses against tumors antigenic markers. Iranian Journal of Basic Medical Sciences, 6(4), 336-345.

5- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R., Zakavi, S.R., Momen-nejad, M., 2004. Evaluation of the clearance characteristics of various microspheres in the human nose by gamma-scintigraphy. International Journal of Pharmaceutics, 280, 125-135.

6- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R.., 2004. Mucosal immunization. Razi, 175, 17-24.

7- Tafaghodi, M., Jaafari, M.R.., Sajadi Tabasi, S.A., 2004. Adjuvants. Razi, 174, 34-45.

8- Sajadi Tabasi, S.A., Tafaghodi, M., Jaafari, M.R., 2004. Dextran microspheres encapsulated with tetanus toxoid as a delivery system for nasal immunization: in vitro and in vivo characterization.  Iranian Journal of Basic Medical Sciences, 7(2), 88-98.

9- Jaafari, M.R., Tafaghodi, M., Sajadi Tabasi, S.A., 2005. Evaluation of the clearance characteristics of liposomes in the human nose by gamma-scintigraphy. Iranian Journal of Pharmaceutical Research, 4(1), 3-11.

10- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R., 2006. Formulation and characterization and release studies of alginate microsphere encapsulated with tetanus toxoid. Journal of Biomaterials Science. Polymer Edition., 17(8), 909-924.

11- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R., 2006. Induction of systemic and mucosal immune responses by intranasal administration of alginate microspheres encapsulated with tetanus toxoid and CpG-ODN. International Journal of Pharmaceutics, 319, 37-43.

12- Tafaghodi, M., Jaafari, M.R., Sajadi Tabasi, S.A., 2006. Nasal immunization studies by liposomes encapsulated with tetanus toxoid and CpG-ODN. European Journal of Pharmaceutics and Biopharmaceutics, 64, 138-145.

13- Tafaghodi, M., Jaafari, M.R., Nikouzadeh, A. 2007. Evaluation of systemic and mucosal immune responses following the nasal immunization by various sizes of liposomes encapsulated with tetanus toxoid. Iranian Journal of Basic Medical Sciences, 9, 4(32), 307-315.

14- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R., 2007. Nasal immunization study by PLGA nanospheres encapsulated with tetanus toxoid and CpG-ODN. Iranian Journal of Pharmaceutical Research, 6(3), 151-158.

15- Ghiasi, Z., Sajadi Tabasi, S.A., Tafaghodi, M., 2007. Preparation and In Vitro  Characterization of Alginate Microspheres Encapsulated with Autoclaved Leishmania major (ALM) and CpG –ODN. Iranian Journal of Basic Medical Sciences, 10(2), 90-98.

16- Tafaghodi, M., Sajadi Tabasi, S.A., Payan, M., 2007. Alginate microspheres as delivery system and adjuvant for autoclaved Leishmania major (ALM) and Quillaja saponin (QS) - Preparation and characterization. Iranian Journal of Pharmaceutical Sciences, 3(2), 61-68.

17- Nazemian, F., Mohammad-Poor, A-H, Naghibi, M, Hasanzadeh-Khayat, M., Tafaghodi, M., Charkazi, S, Abrisham, S., 2007. The effect of pentoxiphylline on hemoglobin levels in patients with erythropoietin resistant anemia in hemodialysis patients. Nephrology Dialysis Transplantation, 22(Supplement 6), 355-355.

18- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R., 2008. Nasal immunization studies by cationic, fusogenic and cationic-fusogenic liposomes encapsulated with tetanus toxoid. Current Drug Delivery, 5, 108-113.

19- Tafaghodi, M., Sajadi Tabasi, S.A., Kharazizadeh, M., 2008. Preparation and characterization of PLGA nanospheres encapsulated with autoclaved Leishmania major (ALM) and Quillaja saponin. Saudi Pharmaceutical Journal, 16(1), 43-49.

20- Sajadi Tabasi, S.A., Tafaghodi, M., Jaafari, M.R., 2008. Induction of high antitoxin titers against tetanus toxoid in rabbits by intranasal immunization with dextran  microspheres. International Journal of Pharmaceutics, 360, 12-17.

21- Tafaghodi, M., Hadizadeh, F., Farahmand, F., 2008. Comparison of spectrophotometry and spectroflourimetry methods in determination of encapsulation efficiencies of TT in microspheres and liposomes, Pharmaceutical Sciences, summer, 53-59.

22- Tafaghodi, M., Sajadi Tabasi, S.A., Amiri, N., 2008. PLGA nanospheres loaded with Autoclaved Leishmania Major (ALM) and CpG-ODN: Preparation and in vitro characterization. Iranian Journal of basic medical Sciences, 11(2), 112-119.

23- Deldar, K., Nazemi, E., Balali Mood, M., Emami, S.A., Mohammadpour, A.H., Tafaghodi, M., Afshari, R., 2008. Effect of Coriandrum sativum L. extract on lead excretion in 3-7 year old children, Journal of Birjand University of Medical Sciences, 15, 11-19.   

24- Amin, M.R., Jaafari, M.R., Tafaghodi, M., 2009. Nasal immunization studies in rabbits by anionic and chitosan coated liposomes encapsulated with tetanus toxoid as a model antigen. Colloids and Surfaces B. Biointerfaces, 74, 225-229.

25- Khadivzadeh, T., Samadi, S., Emami, A., Tafaghodi, M., Sanjar Moosavi, N., Behnam, H.R., 2010. The Effect of Hypericum Perforatum on the Wound Healing and Scar of Cesarean. Journal of Alternative and Complementary Medicine, 16(1), 113-117.

26- Tafaghodi, M., Rastegar, S., 2010. Preparation and in vivo study of dry powder microspheres for nasal immunization. Journal of Drug Targeting, 18(3), 235-242.

27- Emami, S.A., Fakhrjafary, M., Tafaghodi, M., Hassanzadeh, M.K., 2010. Chemical Composition and Antioxidant Activities of the Essential Oils of Different Parts of Cupressus arizonica Greene. Journal of Essential Oil Research, 22, 193-199.

28- Tafaghodi, M., Jaafari, M.R., Eskandari, M., Khamesipour, A., 2010. Immunization against leishmaniasis by PLGA nanospheres loaded with an experimental Autoclaved Leishmania major (ALM) and Quillaja saponins. Tropical Biomedicine, 27, 639-650.

29- Alipour, S., Montaseri, H., Tafaghodi, M., 2010. Preparation and characterization of paclitaxel loaded alginate microparticles for pulmonary delivery. Colloids and Surfaces B. Biointerfaces, 81, 521-529.

30- Mohaghegh, M., Tafaghodi, M., 2011. Dextran microspheres could enhance immune responses against PLGA nanospheres encapsulated with tetanus toxoid and Quillaja saponins after nasal immunization in rabbit. Pharmaceutical Development and Technology, 16, 36-43.

31- Tafaghodi, M., Khamesipour, A., Jaafari, M.R., 2011. Immunization against leishmaniasis by PLGA nanospheres encapsulated with Autoclaved Leishmania major (ALM) and CpG-ODN. Parasitology Research, 108, 1265-1273.

32- Tafaghodi, M., Eskandari, M., Khamesipour, A., Jaafari, M.R., 2011. Alginate microspheres encapsulated with Autoclaved Leishmania major (ALM) and CpG-ODN induced partial protection and enhanced immune response against murine model of leishmaniasis. Experimental Parasitology, 129, 107-114.

 33- Maleki, M., Karimi, G., Tafaghodi, M., Raftari, S., Nahidi, Y., 2012. Comparison of Intralesional 2% zinc sulfate and Glucantime injection in treatment of acute cutaneous Leishmaniasis. Indian Journal of Dermatology, 57, 118-122.

34- Tafaghodi, M., Eskandari, M., 2012. The mucosal adjuvant potential of cross-linked dextran microspheres (CDM) as dry powder. Iranian Journal of Basic Medical Sciences, 15, 873-879.

35- Moghadam Aryaee, F., Tafaghodi, M., 2012. Mucosal adjuvant potential of Quillaja saponins and cross-linked dextran microspheres, co-administered with liposomes encapsulated with tetanus toxoid. Iranian Journal of Pharmaceutical Research, 11(3), 723-732.

36- Khodaverdi, E., Tafaghodi, M., Ganji, F., Abnoos, K., Naghizadeh, H., 2012. In vitro insulin release from thermosensitive chitosan hydrogel.  AAPS PharmSciTech, 13, 460-466.

37- Tafaghodi, M., Saluja, V., Kersten, G.F.A., Kraan, H., Slütter, B., Amorij, J.-P., Jiskoot W., 2012. Hepatitis B surface antigen nanoparticles coated with chitosan and trimethyl chitosan: impact of formulation on physicochemical and immunological characteristics. Vaccine, 30, 5341-5348.

38- Moghimipour, E., Tafaghodi, M., Balouchi, A., Handali, S., 2013. Formulation and in vitro Evaluation of Topical Liposomal Gel of Triamcinolone Acetonide. Research Journal of Pharmaceutical, Biological and Chemical Sciences (RJPBCS), 4, 101-107.

39- Hosseinzadeh, H., Tafaghodi, M., Moosavi, M.J., Taghiabadi, E., 2013. Effect of Aqueous and Ethanolic Extracts of Nigella sativa Seeds on Milk Production in Rats. JAMS Journal of Acupuncture and Meridian Studies, 6, 18-23. 

40- Zarifpour, M., Hadizadeh, F., Iman, M., Tafaghodi, M., 2013. Preparation and characterization of trimethylchitosan (TMC) nanospheres encapsulated with tetanus toxoid. Pharmaceutical Sciences, 1(2), 13-18.

41- Dehghan, S., Tavassoti Kheiri, M., Tabatabaiean, M., Darzi, S., Tafaghodi, M., 2013. Dry-powder form of chitosan nanospheres containing infulenza virus and adjuvants for nasal immunization. Archives of Pharmacal Research, 36:981-992.

42- Ganji, F., Khodaverdi, E., Tafaghodi, M., Sadoogh, M., 2013. Effects of Formulation Properties on Sol-Gel Behavior of Chitosan/glycerolphosphate Hydrogel. Iranian Polymer Journal, 22:785-790.

43- Khodaverdi, E., Tafaghodi, M., Beizaei, S., Abnous, Kh., Alibolandi, M., and Hadizadeh, F., 2013. Preparation and Characterization of PLGA-PEG-PLGA nanospheres prepared with a new thermogelling method for Insulin Delivery. Journal of Chemical and Pharmaceutical Research, 5, 311-319.

44- Khameneh Bagheri, B., Momen-nejad, M., Tafaghodi, M., 2014. In vivo evaluation of mucoadhesive properties of nanoliposomal formulations upon coating with trimethylchitosan polymer. Nanomedicine Journal, 1(3), 147-154.

45- Mohammadpour, A.H., Nazemian, F., Hasanzadeh, M., Tafaghodi, M., Salari, P., Charkazi, S., Naghibi, M., Shamsara, J., 2014. Evaluation of the effect of pentoxifylline on erythropoietin-resistant anemia in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation, 25, 73-78.

46- Razavi Rohani, S.S., Abnous, K., Tafaghodi, M., 2014. Preparation and characterization of spray-dried powders intended for pulmonary delivery of Insulin with regard to the selection of excipients. International Journal of Pharmaceutics, 465, 464-478.

47- Tafaghodi, M., Kersten, G.F.A, Jiskoot, W., 2014. Nano-adjuvanted polio vaccine: Preparation and characterization of chitosan and trimethyl chitosan (TMC) nanoparticles loaded with inactivated polio virus and coated with sodium alginate. Nanomedicine Journal, 1(4), 220-228.

48- Hosseinzadeh, H., Tafaghodi, M., Abedzadeh, S., Taghiabadi, E., 2014. Effect of Aqueous and Ethanolic Extracts of Pimpinella anisum L. Seeds on Milk Production in Rats. Journal of Acupuncture and Meridian Studies, 7(4), 211-216.

49- Ghoochi Atashbeyk, D., Khameneh Bagheri, B., Tafaghodi, M., Fazly Bazzaz, B.S., 2014. Eradication of methicillin-resistant Staphylococcus aureus infection by nanoliposomes loaded with gentamicin and oleic acid. Pharmaceutical Biology, 52 (11), 1423-1428.

50- Mohajer, M., Khameneh, B., Tafaghodi, M., 2014. Preparation and characterization of PLGA nanospheres loaded with inactivated influenza virus, CpG-ODN and Quillaja saponin. 17, 722-726.

51- Khodaverdi, E., Heidari, Z., Sajadi Tabassi, S.A., Tafaghodi, M., Alibolandi, M., Mirzazadeh Tekie, F.S., Khameneh, B., Hadizadeh, F., 2014. Injectable supramolecular hydrogel from insulin-loaded triblock PCL-PEG-PCL copolymer and γ-cyclodextrin with sustained-release property. AAPS PharmSciTech, 16(1), 141-149.

52- Dehghan, S., Tafaghodi, M., Bolourieh, T., Mazaheri, V., Torabi, A., Abnous, KH., Tavassoti Kheiri, M., 2014. Nasal immunaization against influenza by chitosan nanospheres encapsulated with Influenza whole virus and adjuvants in dry-powder form. International Journal of Pharmaceutics, 475, 1-8.

53- Kazemi-Beydokhti, A., Zinali heris, S., Tafaghodi, M., Jaafari, M.R., Hatamipoor, M., 2014. Microwave functionalized single-walled carbon nanotube as nanocarrier for the delivery of anticancer drug cisplatin: in vitro and in vivo evaluation. Journal of Drug Delivery Science and Technology, 24(6), 572-578.

54- Moayedian, T., Mosaffa, F., Khameneh-Bagheri, B., Tafaghodi, M., 2015. Combined effects of PEGylation and particle size on uptake of PLGA particles by macrophage cells. Nanomedicine Journal, 2(4), 299-304.

55- Mehravaran, A., Jaafari, M.R., Jalali, S.A., Khamesipour, A., Tafaghodi, M., Hojatizade, M., Badiee, A., 2015. The role of surface charge of ISCOMATRIX nanoparticles on the type of immune response generated against Leishmaniasis in BALB/c mice. Nanomedicine Journal, 2(4), 249-260.

56- Montaseri, H., Alipour, S., Tafaghodi, M., 2015. Inhalable, large porous PLGA microparticles loaded with pcalitaxel: Preparation, in vitro and in vivo characterization. Journal of Microencapsulation, 32(7), 661-668.

57- Rady Raz, N., Akbarzadeh-T, M.R., Tafaghodi, M., 2015. Bio-inspired Nanonetworks for Targeted Cancer Drug Delivery. IEEE Transaction of Nanobiosience, 14(8), 894-906.

58- Mehravaran, A., Jaafari, M.R., Jalali, S.A., Khamesipour, A., Tafaghodi, M., Hojatizade, M., Badiee, A., 2015. The role of surface charge of ISCOMATRIX nanoparticles on the type of immune response generated against Leishmaniasis in BALB/c mice. Nanomedicine Journal 2 (4), 249-260.

59- Mehravaran, A., Jaafari, M.R., Jalali, S.A., Khamesipour, A., Tafaghodi, M., Hojatizade, M., Abbasi, A., Badiee, A., 2015. Cationic Immune Stimulating Complexes Containing Soluble Leishmania Antigens: Preparation, Characterization and in Vivo Immune Response Evaluation. Iranian Journal of Immunology 12 (4), 274.

60- Radvar, M., Moeintaghavi, A., Tafaghodi, M., Ghanbari, H., Fatemi, H., Mokhtari, M.R., Najafi, F., Hoseinipour, Z., Dastmalchi, P., Farazi, F., 2016. Clinical efficacy of herbal mouth wash composed of Salix alba, Malva sylvestris and Althaea officinalis in chronic periodontitis patients. Journal of Herbal Medicine, 6, 24-27.

61- Shiehzadeh, F., Tafaghodi, M., 2016. Dry powder form of polymeric nanoparticles for pulmonary drug delivery. Current Pharmaceutical Design, 22(17), 2549-2560.

62- Amirnasr, M., Fallah-tafti, T., Sankian, M., Rezaei, A., Tafaghodi, M., 2016. Immunization against HTLV-1 with CHT and TMC nanoparticles loaded with recombinant env23 and env13 antigens of envelope protein gp46. Microbial Pathogenesis, 97, 38-44.

63- Alipour, S., Montaseri, H., Nekouian, A.A., Khalili Azad, A., Mohamadpour, A.H., Tafaghodi, M., 2016. Non-invasive endotracheal delivery of paclitaxel loaded alginate microparticles: pharmacokinetic study. Journal of Chemotherapy (In Press).

64- Tafaghodi, M., Jaafari, M-R. Eskandari, M., Khamesipour, A., 2016. Immunization against cutaneous leishmaniasis by Alginate microspheres loaded with Autoclaved Leishmania major (ALM) and Quillaja saponins. Iranian Journal of Pharmaceutical Research (In Press).

65- Hadizadeh, F., Khodaverdi, E., Javan, M., Tafaghodi, M., Sajadi Tabassi, S.A., Chamani, J., Khameneh, B., Mirzazadeh Tekie, F.S., 2016. Sustained Drug Delivery System for Insulin using Supramolecular Hydrogels Composed of Tri-block Copolymers. Submitted to IJPR.

66- Amini, Y., Moradi, B., Tafaghodi, M., Meshkat, Z., Ghazvini, K., Fasihi-Ramandi, M., 2016. TB trifusion antigen adsorbed on calcium phosphate nanoparticles stimulated strong cellular immunity in mice. Submitted to experimental nanoscience.

67- Karimi, S.M., Sankian, M., Khademi, F., Tafaghodi, M., 2016. Chitosan (CHT) and trimethylchitosan (TMC) nanoparticles as adjuvant/delivery system for parenteral and nasal immunization against Mycobacterium tuberculosis (MTb) ESAT-6 antigen. Submitted to Microbiology and Immunology.

68- Pirouzmand, H., Khameneh, B., Tafaghodi, M., 2016. Evaluation of immunoadjuvant potential of dry powder form of cross-linked dextran microspheres (CDM) mixed with chitosan ‎nanospheres encapsulated with tetanus toxoid, after nasal ‎immunization in rabbits. Submitted to Pharmaceutical Biology.

69- Amini, Y., Tafaghodi, M., Amel Jamehdar, S., Meshkat, Z., Moradi, B., Sankian, M., 2016. Heterologous expression, purification and characterization of the HspX, Ppe44 and EsxV proteins of Mycobacterium tuberculosis as a vaccine candidate in prokaryotic system. Submitted to Asian Pacific Journal of Tropical Medicine.

70- Dehghan, S., Kheiri, M.T., … , Tafaghodi, M., 2016. Dry powder vaccine preparation, characterization and immunogenic evaluation of Alginate-based whole inactivated influenza nasal vaccine in rabbits. Submitted to journal of Colloids and Surfaces B.

71- Mosafer, J., Abnous, Kh., Tafaghodi, M., Ramezani, M., 2016. In vitro and in vivo evaluation of anti-nucleolin-targeted magnetic PLGA nanoparticles loaded with doxorubicin as a theranostic agent for enhanced targeted cancer imaging and therapy. Submitted to ٍEuropean Journal of Pharmaceutics and Biopharmaceutics.

                                                                      Presentations

1- Tafaghodi, M. Shokouhi Nejad, H., 1995. Evaluation of different methods of determination of poor soluble substances. Proceeding of the 2^nd congress of Iranian pharmacy students, Mashhad, Iran.

2- Moghimipour E., Dehghan G. and Tafaghodi M., 1998. The study of HPMC concentrations on physical properties of coated tablets. Proceeding of the 6^th Iranian Congress of Pharmaceutical Sciences, Tehran, Iran.

3- Tafaghodi M., Rahimizadeh M., Hassanzadeh M., 2000. Isolation and characterization of alkaloids of Hyoscyamus insanus. Proceeding of the 7^th Iranian Congress of Pharmaceutical Sciences, Mashhad, Iran.

4- Tafaghodi, M., Jaafari, M.R., Sajadi Tabasi, S.A., 2000. Formulation and characterization of liposomes containing tetanus toxoid. Proceeding of the 7^th Iranian Congress of Pharmaceutical Sciences, Mashhad, Iran.

5- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R., 2002. Preparation and characterization of alginate microspheres encapsulated with tetanus toxoid for nasal delivery. Proceeding of the 8^th Iranian Congress of Pharmaceutical Sciences, Shiraz, Iran.

6- Tafaghodi, M., Diwan, M., Samuel, J., Jaafari, M.R., Sajadi Tabasi, S.A., 2002. Increasing the immune responses by co-delivery of tetanus toxoid and CpG ODN encapsulated in PLGA nanospheres­. Proceeding of the 8^th Iranian Congress of Pharmaceutical Sciences, Shiraz, Iran.

7- Tafaghodi, M., Zakavi, S.R., Sajadi Tabasi, S.A., Jaafari, M.R., Momen Nejad, H., 2002. Gamma-Scintigraphy as a novel method to study the distribution and clearance rate of different mucoadhesive nasal delivery systems. Proceeding of the 6^th Annual Meeting of Nuclear Medicine, Mashhad, Iran.

8- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R.., 2003. Nasal immunization using alginate microspheres encapsulated with tetanus toxoid (TT). Proceeding of the 1^st Congress of New Drug Delivery Systems, Tehran, Iran.

9- Sajadi Tabasi, S.A., Tafaghodi, M., Jaafari, M.R.., 2003. Nasal immunization using cross-linked dextran microspheres encapsulated with tetanus toxoid (TT). Proceeding of the 1^st Congress of New Drug Delivery Systems, Tehran, Iran.

10- Tafaghodi, M., Jaafari, M.R.., Sajadi Tabasi, S.A., 2003. Nasal immunization using neutral, cationic, fusogenic and cationic-fusogenic liposomes encapsulated with tetanus toxoid (TT). Proceeding of the 1^st Congress of New Drug Delivery Systems, Tehran, Iran...

11- Tafaghodi, M., Samuel, J., Diwan, M., Sajadi, S.A., Jaafari, M.R., 2003. Utilization of particulate and immunomodulating adjuvants for enhancement of immune response against tumors antigenic markers. Proceeding of the 3rd Congress of National Biotechnology, Mashhad, Iran.

12- Tafaghodi, M., Sajadi Tabasi, S.A., Jaafari, M.R.., 2006. Nasal immunization studies by alginate and cross-linked dextran microspheres and PLGA nanospheres encapsulated with tetanus toxoid (TT). Proceeding of the 10^th Iranian Congress of Pharmaceutical Sciences, Tehran, Iran.

13- Tafaghodi, M., Sajadi Tabasi, S.A., Kharazizadeh, M., 2007. Preparation and characterization of PLGA nonospheres encapsulated with autoclaved Leishmania major (ALM) and saponin adjuvant. Proceeding of the 3^rd Congress of New Drug Delivery Systems, Tehran, Iran.

14- Tafaghodi, M., Hadizadeh, H., Farahmand, F., 2007. Determination of encapsulation efficiency of fluorescent tetanus toxoid in microsphere and Liposome drug delivery systems by spectrofluorimetery method. Proceeding of the 3^rd Congress of New Drug Delivery Systems, Tehran, Iran.

15- Tafaghodi, M., Jaafari, M.R., Amin, M.R., 2007. Nasal Immunization Studies in Rabbits by Anionic and Chitosan Coated Liposomes Encapsulated with Tetanus Toxoid as a Model Antigen. Proceeding of the 1^st Vaccine Congress, Amsterdam, Netherland.

16- Tafaghodi, M., Jaafari, M.R., Sajadi Tabasi, S.A., 2008. Preparation, characterization and immunization studies with PLGA nonospheres encapsulated with autoclaved Leishmania major (ALM) and saponin adjuvant. Proceeding of the 11^th Iranian Congress of Pharmaceutical Sciences, Kerman, Iran.

17- Tafaghodi, M., 2009. Nanoparticulate drug delivery systems as vaccine adjuvant and delivery system. Proceeding of the Nanodrugs, nano-biotechnology, nano-biosensors and nano-materials in medical sciences. Mashhad, Iran.

18- Tafaghodi, M., Jaafari, M.R., Sajadi, S.A., Khamesipour, A., Amiri, N., 2009. Immunization against leishmaniasis by PLGA nanospheres encapsulated with autoclaved Leishmania major (ALM) and CpG-ODN. ICRC 2009, Zanjan, Iran.

19- Tafaghodi, M., Mohaghegh, M., 2009. Dextran microspheres could enhance immune responses against PLGA nanospheres encapsulated with tetanus toxoid and Quillaja saponins after nasal immunization in rabbit. ICRC 2009, Zanjan, Iran. 

20- Tafaghodi, M., Jaafari, M.R., Sajadi Tabasi, S.A., 2009. Induction of immune responses against leishmaniasis by alginate microspheres encapsulated with autoclaved Leishmania major (ALM) antigen and CpG-ODN.  Proceeding of the 3^rd Modern vaccine adjuvant and delivery systems, Vienna, Austeria.

21- Tafaghodi, M., Jiskoot, W., Saluja, V., 2011. Hepatitis B surface antigen (HBsAg) nanoparticles coated with chitosan and trimethyl chitosan (TMC): impact of formulation on physicochemical and immunological characteristics.

22- Tafaghodi, M., 2016. Polymer based nanoparticles as adjuvant/vaccine delivery system for systemic and mucosal immunizations. 13^th International Congress of Immunology and allergy of Iran. Tabriz, Iran.

                                                                    Honors & Awards

Honored investigator (student) in medicinal sciences, Ferdowsi Festival, Mashhad, 2001 (Offered by MUMS and FUM).

Honored Pharmacist, Mashhad, 2002 (Offered by Khorasan Association of Pharmacists).

The best presentation in 8^th Iranian Seminar of Pharmaceutical Scientists (Ph.D. student), Shiraz, 2002 (Offered by Iranian Association of Pharmaceutical Scientists).

Honored young researcher, 9^th Iranian Seminar of Pharmaceutical Sciences, Tabriz, 2004 (Offered by Iranian Association of Pharmaceutical Scientists).

The best book translation (Adverse effects of herbal drugs vol. 1 and 2), Research week festival, Mashhad, 2004 (Offered by MUMS)

Three awards from Iranian Nanotechnology Initiative for supervision of two Pharm.D. thesis.

The best book translation (Pharmaceutics, vol. 1), Research week festival, Mashhad, 2006 (Offered by MUMS)

Honored lecturer, MOALEM week festival, Mashhad, 2007 (Offered by MUMS)

The best book translation (Pharmaceutics, vol. 2), Research week festival, Tehran, 2007 (Offered by University of Tehran)

The best book translation (Pharmaceutics, vol. 2), Research week festival, Mashhad, 2007 (Offered by MUMS)

The best presentation in ICRC 2011, Mashhad, 2011 (Offered by Iranian Controlled Release Society).

The best book translation (Nonprescription Drug Therapy), Research week festival, Mashhad, 2011 (Offered by MUMS)

The best book translation (Pharmaceutics, vol. 1), Research week festival, Mashhad, 2015 (Offered by MUMS).

Members                                                  hip Membership

Member of “Nanotechnology Research Center”, Mashhad University of Medical Sciences

Member of “Pharmaceutical Research Center”, Mashhad University of Medical Sciences

Member of “Controlled Release Society of Iran”

Editorial member of Asian Pacific Journal of Tropical Medicine (2009-2011)

Editorial member of Nanomedicine Journal

Reviewer of Drug Development and Industrial Pharmacy journal

Reviewer of Journal of Drug Targeting

Reviewer of Journal of Microencapsulation

Reviewer of Journal of the Taiwan Institute of Chemical Engineers

Reviewer of Iranian Journal of Pharmaceutical Research

Reviewer of Iranian Journal of Basic Medical Sciences

Reviewer of DARU journal

Reviewer of Colloids and Surfaces, B journal

                                                           Administrative Responsibilities

Other Skills

Sayyed Abolghassem Sajadi Tabassi

(Pharm.D., Ph.D.)

Professor of Pharmaceutics

Address:

School of Pharmacy

Mashhad University of Medical Sciences (MUMS)

P O Box 1365-91775

Mashhad, I.R. Iran

Tel: (0098 511) 8823255-66

Fax: (0098 511) 8823251

sajadia[at]mums.ac.ir

sajaditabassi[at]yahoo.com

This email address is being protected from spambots. You need JavaScript enabled to view it.

Updated at: 20/06/2016                          

                                                       und Educational Background

1992-96 (Ph.D. in Pharmaceutics), Department of Pharmacy, King’s College London, University of London, London, UK; Supervisors: Professor Gary P. Martin and Professor Christopher Marriott.

1976-83 (Pharm.D.) School of Pharmacy, Ferdowsy University of Mashhad (presently “Mashhad University of Medical Sciences”), Mashhad, I.R. Iran. The final two years (1981-1983) including the thesis passed in the Faculty of Pharmacy, Tehran University of Medical Sciences; Supervisor: Professor Ayenehchi.

                                                                   Research Interests

1. Investigation of the effect of drugs and excipients on biological membranes
2. Preparation and characterization of drug loaded microspheres and nanospheres
3. Investigation of physico-chemical properties and absorption enhancing effects of plant saponins
4. Mucosal delivery of peptides and proteins e.g. Cyclosporine, Insulin and protein antigens
5. Isolation and purification of mucin glycoproteins from various mucosal surfaces and study of the effects of drugs and excipients on mucus rheology and structure

                                                                       Publications

A- International Journals:

1. Sajadi Tabassi S. A., Martin G.P., Marriott C. (2001) the effects of polysorbate surfactants on the structure of mucus glycoproteins. DARU, 9 (1&2), 6-11.
2. Sajadi Tabassi S.A., Razavi N. (2003) Preparation and characterization of albumin microspheres encapsulated with propranolol HCl. DARU, 11(4), 137-141.
3. Tafaghodi, M., Sajadi Tabassi, S.A., Jaafari, M.R. (2004) Evaluation of the clearance characteristics of various microspheres in the human nose by gamma-scintigraphy. Int J. Pharm., 280, 125-135.
4. M. Tafaghodi,  M. R. Jaafari, S. A. Sajadi, J. Samuel, M. Diwan (2004) Utilization of particulate and immunomudulating adjuvants for enhancement of immune response against tumors’ antigenic markers. Ir. J. Basic Med. Sci., 6(4), 278-285.
5. Sajadi Tabassi S.A., Hosseinzadeh H., Ramezani M., Moghimipour E., Mohajeri S.A. (2006)

Isolation, characterization and study of enhancing effects on nasal absorption of insulin in rat of the total saponin from Acanthophyllum squarrosum. Current Drug Delivery, 3 (4), 399-404

1. Moghimipour E., Jalali A., Sajadi Tabassi S.A., Loebenberg R. (2004) The enhancing effect of sodium glycocholate and sodium salicylate on rat’s gastrointestinal permeability to insulin. Iranian J. Pharm. Res., 3(2), 87-91.
2. M. TAFAGHODI, S. A. SAJADI TABASI, M. R. JAAFARI (2006) Formulation, characterization and release studies of alginate microspheres encapsulated with tetanus toxoid. J. Biomater. Sci. Polymer Edn., 17 ( 8), 909–924.
3. Malaekeh-NikouEI B., Sajadi tabassi S.A., Jaafari M.R. (2006) The effect of different grades of PLGA on characteristics of microspheres encapsulated with Cyclosporine A. Current Drug Delivery, 3 (4), 343-349.
4. Bizhan Malaekeh-Nikouei, Sayyed A. Sajadi Tabassi, Mahmoud R. Jaafari, Nigel M. Davies (2006) Preparation and characterization of PLGA microspheres loaded with cyclosporine-cyclodextrin complex., Iranian Journal of Pharmaceutical Sciences, 1(4): 191-198.
5. Tafaghodi, M., Sajadi Tabassi, S.A., Jaafari, M.R. (2006) Induction of systemic and mucosal immune responses by intranasal administration of alginate microspheres encapsulated with tetanus toxoid and CpG-ODN. International Journal of Pharmaceutics 319, 37–43.
6. Mohsen Tafaghodi, Sayyed A Sajadi Tabassi, Nafiseh Amiri (2008) PLGA Nanospheres loaded with Autoclaved Leishmania Major (ALM) and CPG-ODN: Preparation and in-vitro Characterization. Iranian J Basic Med. Sci., 11(2), 112-119.
7. Mohsen Tafaghodi, Mahmood-Reza Jaafari, Sayyed Abolghasem Sajadi Tabassi (2008) Nasal Immunization Studies by Cationic, Fusogenic and Cationic-fusogenic Liposomes Encapsulated With Tetanus Toxoid. Current Drug Del., 5, 108-113
8. Bizhan Malaekeh-Nikouei, Sayyed A. Sajadi Tabassi, Mahmoud R. Jaafari (2007) Preparation, characterization and mucoadhesive evaluation of chitosan coated liposomes containing cyclosporine A. Saudi Pharmaceutical Journal, 15 (3-4), 176-182
9. Malaekeh-Nikouei B., Sajadi S. A., Jaafari M. R. (2008), Preparation, characterization and mucoadhesive properties of chitosan coated microspheres encapsulated with cyclosporine A, Drug Development and Industrial Pharmacy, 34, 5, 492-498.
10. Mohsen Tafaghodi_, S. Abolghasem Sajadi Tabassi, Maria Kharazizadeh (2008) Preparation and characterization of PLGA nanospheres encapsulated with autoclaved Leishmania major (ALM) and Quillaja saponin. Saudi Pharmaceutical Journal, 16 (1), 43-49.
11. S. Abolghasem Sajadi Tabassi, Mohsen Tafaghodi, Mahmoud Reza Jaafari (2008) Induction of high antitoxin titers against tetanus toxoid in rabbits by intranasal immunization with dextran microspheres, International Journal of Pharmaceutics, 360, 12-17.
12. Bizhan Malaekeh-Nikouei , Mahmoud R. Jaafari, Sayyed A. Sajadi Tabassi , Afshin Samiei (2008) The enhancement of immunosuppressive effects of cyclosporine A on human T-cells using fusogenic liposomes. Colloids and Surfaces B: Biointerfaces, 67, 238-244.
13. N. Khadem, S. A. Sajadi Tabassi, N. Ghomian, F. Eftekharzadeh (2008) Comparison of Boric Acid with Clotrimazole in the Treatment of Recurrent or Resistant Vulvovaginitis Caused by Non-Albicans Species of Candida. Iranian Journal of Medical Sciences (IJMS), Vol 33, No 4, 226-230.
14. P.  Ebrahimnejad, S. A. Sajadi Tabassi, M. R. Jaafari, F. Atyabi, F. Ramezani Ghara, R. Dinarvand (2009) Preparation and characterization of poly lactide-co-glycolyde nanoparticles of SN-38. PDA Journal of Pharmaceutical Science and Technology, vol. 63 no. 6, 512-520.
15. Bizhan Malaekeh-Nikouei, Sayyed A. Sajadi Tabassi, Hossein Ashari, Ali Gholamzadeh (2009) Evaluation the effect of cyclodextrin complexation on aqueous solubility of fluorometholone to achieve ophthalmic solution. J Incl Phenom Macrocycl Chem, 65, 335-340.
16. P. Ebrahimnejad, R. Dinarvand, S. A. Sajadi Tabassi, M. R. Jaafari, F. Atyabi (2009) Development and validation of an ion-pair HPLC chromatography for simultaneous determination of lactone and carboxylate forms of SN-38 in nanoparticles. Journal of food and drug analysis, 17 (4), 246-56.
17. Pedram Ebrahimnejad, Rassoul Dinarvandad, Abolghasem Sajadi, Mahmoud Reza Jaafari, Ali Reza Nomani, Ebrahim Azizi, Mazda Rad-Malekshahi, Fatemeh Atyabia (2010) Preparation and in vitro evaluation of actively targetable nanoparticles for SN-38 delivery against HT29 cell lines. Journal of Nanomedicine, Nanotechnology, Biology and Medicine, Volume 6, Issue 3, June 2010, Pages 478-485
18. Pedram Ebrahimnejad, Rassoul Dinarvand, Mahmoud Reza Jaafari, Seyed Abolghasem Sajadi Tabasi, Fatemeh Atyabi (2010) Characterization, blood profile and biodistribution properties of surface modified PLGA nanoparticles of SN-38. International Journal of Pharmaceutics, Volume 406, Issues 1-2, March 2011, Pages 122-127
19. Bizhan Malaekeh-Nikouei, Sayyed A. Sajadi Tabassi, Golara Gerayeli, Mehran Arab Salmani, Ali Gholamzadeh (2012) The effect of cyclodextrin mixtures on aqueous solubility of beclomethasone dipropionate. J Incl Phenom Macrocycl Chem (2012) 72:383–387
20. Eskandar Moghimipour, Sayyed Abolghassem Sajadi Tabassi, Maryam Kouchak and Hadi Varghaei (2012) Combination Strategies for Enhancing Transdermal Absorption of Theophylline through Shed Snake Skin. Asian Journal of Pharmaceutical and Clinical Research, 5(2), 30-34
21. Sayyed Abolghasem Sajadi Tabassi, Seyedeh Vida Hashemi, Seyed Ahmad Mohajeri (2013) Dummy template molecularly imprinted polymer for omeprazole and the study of its drug binding and release properties. Journal of Applied Polymer Science, Volume 130, Issue 6, December 15, 2013, Pages: 4165–4170 (IF=1.64).
22. Elham Khodaverdi, Farnaz Sadat Mirzazadeh Tekie, Farzin Hadizadeh, Haydar Esmaeel, Seyed Ahmad Mohajeri, Sayyed A. Sajadi Tabassi and Gholamhossein Zohuri (2013) Hydrogels Composed of Cyclodextrin Inclusion Complexes with PLGA-PEG-PLGA Triblock Copolymers as Drug Delivery Systems. AAPS PharmSciTech, 15 (1), 177-188 (IF=1.584).
23. Sayyed A. Sajadi Tabassi,  Farnaz Sadat Mirzazadeh Tekie, Farzin Hadizadeh, Rahof Rashid, Elham Khodaverdi, Seyed Ahmad Mohajeri (2014) Sustained release drug delivery using supramolecular hydrogels of the triblock copolymer PCL–PEG–PCL and α-cyclodextrin. Journal of Sol-Gel Science and Technology. 69 (1), 166-171, (IF=1.66).
24. Seyed Amin Mohajeri, Sayyed Abolghasem Sajadi Tabassi, Maryam Hassanpour Moghadam, Seyed Ahmad Mohajeri (2014) Preparation of a pH-sensitive pantoprazole-imprinted polymer and evaluation of its drug-binding and -releasing properties. Science China Chemistry, Vol.57, No.6: 857–865 (IF=1.327) (doi: 10.1007/s11426-014-5091-1).
25. Elham Khodaverdi,  Zinat Heidari, Sayyed A. Sajadi Tabassi, Mohsen Tafaghodi, Mona Alibolandi, Farnaz Sadat Mirzazadeh Tekie, Bahman Khameneh, and Farzin Hadizadeh (2014) Injectable Supramolecular Hydrogel from Insulin-Loaded Triblock PCL-PEG-PCL Copolymer and γ-Cyclodextrin with Sustained-Release Property. AAPS PharmSciTech, (doi: 10.1208/s12249-014-0198-4) (IF=1.584).
26. Ali Talaei, Maryam Hassanpour Moghadam, Sayyed Abolghasem Sajadi Tabassi, Seyed Ahmad Mohajeri (2015) Crocin,the main active saffron constituent, as an adjunctive treatment in major depressive disorder: A randomized, double-blind, placebo-controlled, pilot clinical trial. Journal of Affective Disorders, 174, 51-56 (IF = 3.705)
27. Elham Khodaverdi • Maryam Aboumaashzadeh • Farnaz Sadat Mirzazadeh Tekie • Farzin Hadizadeh • Sayyed Abolghasem Sajadi Tabassi • Seyed Ahmad Mohajeri • Zahra Khashyarmanesh • Hamideh Moallemzadeh Haghighi (2014) Sustained drug release using supramolecular hydrogels composed of cyclodextrin inclusion complexes with PCL/PEG multiple block copolymers. Iranian Polymer Journal, 23, 707-716 (IF=0.936)

11.  Jaafari, M.R., Tafaghodi, M., Sajadi Tabassi, S.A., (2005) Evaluation of the clearance characteristics of liposomes in the human nose by gamma-scintigraphy. Iranian J. Pharm. Res., 4(1), 3-11.

12.  Bizhan Malaekeh-Nikouei, Sayyed A. Sajadi Tabassi, Mahmoud R. Jaafari, Nigel M. Davies (2006) The effect of complexation on characteristics and drug release from PLGA microspheres loaded by cyclosporine-cyclodextrin complex. Journal of Drug Delivery Science and Technology, 16(5), 345-350.

13.  Mohsen Tafaghodi, Mahmood-Reza Jaafari, Sayyed Abolghasem Sajadi Tabassi(2006) Nasal immunization studies using liposomes loaded with tetanus toxoid and CpG-ODN. European Journal of Pharmaceutics and Biopharmaceutics 64, 138–145.

14.  Mohsen Tafaghodi, Sayyed Abolghasem Sajadi Tabassi, Mahmood-Reza Jaafari (2007) Nasal immunization study by PLGA nanospheres encapsulated with tetanus toxoid and CpG-ODN. Iranian J. Pharm. Res. 6 (3), 151-158

B- National Journals:

1. Sajadi Tabassi S. A., Mamaghani Sani D. (2001) Investigation of the effects of ionic surfactants on biological membranes using human erythrocytes as a model. Ir. J. Basic Med. Sci. 4, 2, 89-94.
2. Sajadi Tabassi S. A., Shafiee Nik R., Rajabi O., Abbaspour M. R., (2002) A new oral solid dosage form of insulin: releaSe and stabIlity  studies. Ir. J. Basic Med. Sci., 5 (2), 75-81.
3. Moghimipour E., Sajadi Tabassi S.A., Ramazani M., Loebenberg R. (2002) Enhanced permeability of gentamicin sulfate through snake skin and liposomal membranes by different enhancers. Ir. J. Basic Med. Sci., 6 (1), 9-19.
4. Tafaghodi M., Sajadi Tabassi S.A., Jaafari M.R. (2002) Formulation, characteriazation and release studies of alginate microsphere encapsulated with tetanus toxoid for nasal immunization. Ir. J. Basic Med. Sci., 6(1), 20-31.
5. Tafaghodi M., Sajadi Tabassi S.A., Jaafari M.R. (2002) Nasal drug delivery: characteristics and limitations. Razi Pharmaceutical Journal, 11, 32-42.
6. Sajadi Tabassi S.A., Hosseinzadeh H., Mohajeri S.A. (2003) Absorption enhancing effects of Acanthophyllum total saponin on intranasal insulin in rat. Iranian Journal of Diabetes and Lipid Disorders, vol 2, No 1, 17-24.
7. Sajadi Tabassi S.A., Jaafari M.R., Tafaghodi M., Diwan M., Samuel J. (2003) Enhancement of immune responses following co-administration of CpG oligodeoxynucleotide (CpG-ODN) and tetanus toxoid in PLGA microspheres. Ir. J. Basic Med. Sci., 6 (3), 221-236.
8. Sajadi Tabassi, S.A., Naniroudi, M.A. (2004) Investigation of the effects of polysorbate non-ionic surfactants on biological membranes using human erythrocytes as a model. Ir. J. Basic Med. Sci., 7(3), 157-162.
9. Sajadi Tabassi, S. A., Tafaghodi, M., Jaafari, M. R. (2004) Dextran microspheres containing tetanus toxoid as a potential delivery system for nasal immunization: in vitro and in vivo characterization. Ir. J. Basic Med. Sci., 7(2), 88-98.
10. Tafaghodi M., Sajadi Tabassi S.A., Jaafari M.R. (2004) Mucosal immunization. Razi Pharmaceutical Journal, 175, 17-24.
11. Malaekeh, B., Sajadi Tabassi S.A., Jaafari M.R. (2004) Preparation of biodegradable microspheres encapsulated with Cyclosporine A and evaluation of some factors affecting encapsulation efficiency. Ir. J. Basic Med. Sci., 7(4), 240-249.
12. Tafaghodi M., Sajadi Tabassi S.A., Jaafari M.R. (2004) Vaccine Adjuvants. Razi Pharmaceutical Journal. 174, 34-45.
13. Malaekeh-Nikouei, B., Jaafari M.R., Sajadi Tabassi S.A., Samiee A. (2005) Preparation of fusogenic liposomes encapsulated with cyclosporine A and evaluation of its immunosuppressive effects on human T-cells. Pharmaceutical Sciences (Tabriz), Summer 2005, 1-9.
14. Zahra Ghiassi, S. Abolghasem Sajadi Tabassi, Mohsen Tafaghodi (2007) Preparation and characterization of alginate microspheres encapsulated with autoclaved Leishmania major (ALM) and CpG-ODN. Iranian J. Basic Med. Sci., 10 (2), 90-98.
15. Tafaghodi M., Sajadi Tabassi S.A., Payan M. (2008) Alginate microspheres as a delivery system and adjuvant for autoclaved Leishmania major (ALM) and Quillaja saponin (QS) - Preparation and characterization”,  Iranian J. Pharm. Sci., 3(2), 61-68.
16. Hossein Hosseinzadeh, Abolghasem Sajadi Tabassi, Negar Moghadam Milani, Marzieh Rashedinia, Soghra Mehri (2012) Antioxidant Activity of Pistacia vera (pistachio) Fruits, Leaves and Gum Extracts. Iranian Journal of Pharmaceutical Research (IJPR), 11 (3), 879-887, ISI, IF=0.637
17. Jebraeel Movaffagh, Ali Ghodsi, BiBi S. Fazly Bazzaz, Sayyed A. Sajadi Tabassi, Hamideh Ghodrati Azadi (2012) The Use of Natural Biopolymer of Chitosan as Biodegradable Beads for Local Antibiotic Delivery: Release Studies. Jundishapoor Journal of Natural Pharmaceutical Products. 8 (1), 27-33
18. Aazam Parnan Emamverdikhan, Nahid Golmakani, Noorieh Sharifi Sistani, Mohammad Taghi Shakeri, Malihe Hasanzade Mofrad, Abolghasem Sajadi Tabassi (2014) Comparing Two Treatment Methods of Vitamin E Suppository and Conjugated Estrogen Vaginal Cream on the Quality of Life in Menopausal Women with Vaginal Atrophy. J. Midwifery Reprod. Health; 2 (4): 253-260.
19. دکتر ناهید گلمکانی، اعظم پرنان اماموردیخان، دکتر ملیحه حسن زاده  مفرد، دکتر ابوالقاسم سجادی طبسی، دکتر نوریه شریفی سیستانی، دکتر محمد تقی شاکری (1393) مقایسه شاخص های بالینی و آزمایشگاهی در تعیین آتروفی واژن زنان یائسه. مجله زنان، مامایی و نازایی ایران، دوره هفدهم، شماره 501 ، صفحه 17-10

                                                                      Presentations

C- Selected Meeting Abstracts:

1-      Sajadi Tabassi S.A., Moghimipour E., Ramezani M. (2000) Study of physico-chemical properties and hemolytic effects of the total saponin of Acanthophyllum squarrosum. Proc. The 1^st Int. Cong. Trad. Med. Mat. Medica, Nov 2000, Tehran, I.R. Iran

2-      Sajadi Tabassi S.A., Moghimipour E., Ramezani M. (2000) Isolation and determination of surface activity of the total saponin of Acanthophyllum squarrosum. Proc. 7^th Iranian Seminar of Pharmaceutical Sciences. Sep 2000, Mashhad, I.R. Iran

3-      Sajadi Tabassi S.A. (2001) Isolation, purification and rheological characterization of mucus glycoproteins. Proc. The 1^st Seminar on Pharmaceutical Methodology, Sep 2001, Mashhad, I.R. Iran

4-      Tafaghodi M., Jaafari M.R., Sajadi Tabassi S.A. (2000) Formulation and characterization of liposomes encapsulates with tetanus toxoid. Proc. 7^th Iranian Seminar of Pharmaceutical Sciences. Sep 2000, Mashhad, I.R. Iran

5-      Sajadi Tabassi S.A., Abedi H. (2001) Study of the hemolytic effects of antihistamines. Proc. The 1^st Seminar on Pharmaceutical Methodology, Mashhad, I.R. Iran

6-      Sajadi Tabassi S.A., Khalessi B., Ayatollahi S. (2001) Drug induced hemolysis: Phenothiazines and tricyclic antidepressants. Proc. 15^th I. Phys. Pharmacol. Cong., Shiraz, I.R. Iran, p517

7-      Sajadi Tabassi S.A., Ramazani M., Moghimipour E. (2001) Determination of physico-chemical properties and membrane disrupting effects of the total saponin derived from Acanthophyllum squarrosum root. Proc. British Pharmaceutical Conference, Glasgow, UK, p 178

8-      Sajadi Tabassi S.A., Razavi N. (2002) Preparation and characterization of albumin microspheres encapsulated with propranolol HCl. J. Pharm. Pharmacol., 54, S93, Manchester, UK

9-      Ramezani M., Moghimipour E., Sajadi Tabassi S.A., Loebenberg R. (2002) Enhanced permeability of snake skin model using total saponins of Acanthophyllum squarrosum. Proc. World Congress of Pharmacy, FIP 2002, Nice France

10-  Moghimipour E., Sajadi Tabassi S.A., Ramezani M., Loebenberg R. (2002) The enhancement effect of Acanthophyllum squqrrosum total saponin on nasal absorption of gentamicin sulfate. Proc. 8^th Iranian Seminar of Pharmaceutical Sciences, Shiraz, I.R. Iran, p131

11-  Tafaghodi M., Divan M., Samuel J., Jaafari M.R., Sajadi Tabassi S.A. (2002) Increasing the immune responses by co-delivery of tetanus toxoid and CpG ODN encapsulated in PLGA nanospheres. Proc. 8^th Iranian Seminar of Pharmaceutical Sciences, Shiraz, I.R. Iran, p235

12-  Tafaghodi M., Sajadi Tabassi S.A., Jaafari M.R. (2002) Preparation and characterization of alginate microspheres encapsulated with tetanus toxoid for nasal delivery. Proc. 8^th Iranian Seminar of Pharmaceutical Sciences, Shiraz, I.R. Iran, p236

13-  Tafaghodi M., Zakavi S.R., Sajadi Tabassi S.A., Jaafari M.R., Momen-Nejad M. (2002) Gamma-scintigraphy as a novel method to study the distribution and clearance rate of different mucoadhesive nasal delivery systems. Proc. 6^th Ann. Meeting Nucl. Med. Iran, Oct 2002, Mashhad. I.R. Iran

14-  Tafaghodi, M., Sajadi Tabassi, S.A., Jaafari, M.R.. (2003) Nasal immunization using alginate microspheres encapsulated with tetanus toxoid (TT). Proc. the 1^st Congress on Novel Drug Delivery Systems, Tehran, I.R. Iran.

15-  Sajadi Tabassi, S.A., Tafaghodi, M., Jaafari, M.R.. (2003) Nasal immunization using cross-linked dextran microspheres encapsulated with tetanus toxoid (TT). Proc. the 1^st Congress on Novel Drug Delivery Systems, Tehran, I.R. Iran.

16-  Tafaghodi, M., Jaafari, M.R.., Sajadi Tabassi, S.A.( 2003) Nasal immunization using neutral, cationic, fusogenic and cationic-fusogenic liposomes encapsulated with tetanus toxoid (TT). Proc. the 1^st Congress on Novel Drug Delivery Systems, Tehran, I.R. Iran.

17-  Moghimipour E., Ramazani M., Sajadi Tabassi S.A., Loebenberg R. (2003) The enhancing effect of sodium glycocholate and sodium salicylate on the permeability of insulin in rats. Proc. the 1^st Congress on Novel Drug Delivery Systems, Tehran, I.R. Iran.

18-  Sajadi Tabassi, S.A., Hosseinzadeh, H., Mohajeri, S.A. (2003) Investigation of absorption enhancing effect of Acanthophyllum total saponin on intranasal delivery of insulin and blood glucose levels in rat. J. Pharm. Pharmacol. 55 (supplement), S42

19-  Tafaghodi M., Samuel J., Divan M., Sajadi Tabassi S.A., Jaafari M.R. (2003) Utilization of particulate and immunomudulating adjuvants for enhancement of immune response against tumors’ antigenic markers. Proc. 3^rd Ir. Conf. Biotech., Mashhad, I.R. Iran

20-  Sajadi Tabassi, S.A., Tafaghodi, M., Jaafari, M. R. (2004) Dextran microspheres as a potential delivery system for nasal immunization – in vitro and in vivo characterization. Proc. Intl. Meeting on Pharm., Biopharm. Pharm. Tech., Nürenberg Messe, Nuremberg, Germany

21-  Sajadi Tabassi, S.A., Tafaghodi, M., Jaafari, M.R., Zakavi, S.R., Momennejad, M. (2004) Gamma-scintigraphic evaluation of the clearance characteristics of microspheres in human nose. Proc. 3^rd Pharm. Sci. World Cong., Kyoto, Japan

22-  Sajadi Tabassi, S.A., Jaafari, M.R. Shokouhi M. (2004) Preparation and characterization of alginate microspheres loaded with insulin. Proc. 9^th Iranian Seminar of Pharmaceutical Sciences, Tabriz, I.R. Iran, p 5

23-  Sajadi Tabassi, S. A., Ramezani, M., Jassemi Moghadam, M., (2004) Investigation of Physicochemical Properties and Membrane Effects of the Total Saponins Isolated from Acanthophyllum sordidum. Proc. 3^rd Intl. Cong. Health, Environment Nat. Prod., Mashhad. I.R. Iran, p132

24-  Sajadi Tabassi, S. A., Ramezani, M., Mashhadi, T., (2005) Extraction and investigation of physicochemical properties and membrane effects of total saponin from Acanthophyllum korshinskyi. Proc. 1^st Seminar of Med. and Nat. Prod. Chem., Shiraz, I.R. Iran, N 96

25-  Sajadi Tabassi, S.A., Malaekeh-Nikouei, B., Jaafari, M.R. (2005) Preparation and characterization of biodegradable microspheres encapsulated with Cyclosporine A using different grades of PLGA. 1^st PharmSciFair, Nice, France, P O 238

26-  Sayyed Abolghassem Sajadi Tabassi, Mohsen Tafaghodi, Mahmoud Reza Jaafari (2005) Evaluation of the effect of some mucoadhesive microspheres on human nasal mucociliary clearance by Gamma-scintigraphy. Proc. 17^th Congress of Physiology and Pharmacology of Iran, Kerman.

27-  Sajadi Tabassi, S.A.; Mashhadi, T.; Ramazani, M. (2006) Isolation and investigation of surface activity, membrane toxicity and absorption enhancing effects of the total saponins from Acanthophyllum korshinskyi. Proc. The Tenth International Symposium on Oncolog Pharmacy Practice (ISOPP-X), Kuala Lumpur, Malaysia, Journal of Oncology Pharmacy Practice, 12 (1), Poster 5.

28-  Sajadi Tabassi, S.A., Malaekeh-Nikouei, B., Jaafari, M.R., Davies N. (2006) The effect of complexation on characteristics of and drug release from PLGA microspheres loaded by cyclosporine-cyclodextrin complex. The 33 rd Annual Meeting of the Controlled Release Society, Vienna, Austria. (Poster)

29-  Sajadi Tabassi, S.A., Malaekeh-Nikouei, B., Jaafari, M.R., Davies N. (2006) Preparation and characterization of PLGA microspheres loaded by cyclosporine-cyclodextrin complex. Proc. 10^th Iranian Conference of Pharmaceutical Sciences. Tehran, Iran, Aug 2006. Oral Presentation

30-  S. A. Sajadi Tabassi, M. Tafaghodi, M. R. Jaafari (2007) Nasal Immunization Studies by Cationic, Fusogenic and Cationic-fusogenic Liposomes Encapsulated with Tetanus Toxoid. The 9^th Commonwealth Pharmaceutical Association Conference, Kuala Lumpur, Malaysia, (poster).

31-  M. Tafaghodi, M. Kharazizadeh, S. A. Sajadi, Preparation and characterization of PLGA nonospheres encapsulated with autoclaved Leishmania major (ALM) and saponin adjuvant. The 3^rd   Iranain Conference of Novel Drug Delivery Systems, June 2007, Tehran, Iran, O-14.

32-  P. Ebrahimnejad, R. Dinarvand, S.A. Sajadi, F. Atyabi,  Preparation and Characterization of Betamethasone – Loaded PLGA Nanoparticales. The 3^rd   Iranain Conference of Novel Drug Delivery Systems, June 2007, Tehran, Iran. P-13.

33-  B. Malaekeh-Nikouei  , M. R. Jaafari  , S. A. Sajadi Tabassi, Preparation, Characterization and Evaluation of Mucoadhesive and Immunosuppressive Properties of Chitosan Coated Liposomes Encapsulated with Cyclosporine A. The 3^rd Iranain Conference of Novel Drug Delivery Systems, June 2007, Tehran, Iran. P- 42.

34-  S. A. Sajadi Tabassi., Application of Ethics in Pharmacy., The 2^nd International Congress of 7Medical Ethics of Iran, April 2008, Tehran University of Medical Sciences, Tehran, Iran, pp 274-276. Oral

35-  S. A. Sajadi Tabassi, M. Tafaghodi, M. R. Jaafari, Nasal immunization study by PLGA nanospheres encapsulated with tetanus toxoid and CpG-ODN., 2^nd International Congress on Nanoscience and Nanotechnology, October 2008, University of Tabriz, Tabriz, Iran, O-83, Oral

36-  S. A. Sajadi Tabassi, A. Eliaspour; STUDY OF TRANSDERMAL DELIVERY OF AMITRIPTYLINE AND THE EFFECT OF SOME PENETRATION ENHANCERS., 22nd Federation of Asian Pharmaceutical Associations (FAPA) Congress, Nov 2008, Singapore, P-70

37-  P. Ebrahimnejad, F. Atyabi, S.A. Sajadi Tabassi, F. Movaghari, R. Dinarvand; A Novel HPLC Method for Assay of SN-38 in Nanoparticles., 2^nd International Congress on Nanoscience and Nanotechnology, October 2008, University of Tabriz, Tabriz, Iran, Poster

38-  S. A. Sajadi Tabassi , M. Tafaghodi_,  M. Kharazizade; PLGA nanospheres loaded by autoclaved Leishmania major (ALM) and Quillaja saponin as adjuvant: a tentative vaccine against Leishmaniasis, 2^nd Iran-India Joint Conference on Nanotechnology (IIJCN-2009), University of Isfahan, 5-7 May 2009, Iran, Poster.

39-  S. A. Sajadi Tabassi, P. Ebrahimnejad, M. R. Jaafari, F. Atyabi, R. Dinarvand; Encapsulation of SN-38, a novel anticancer drug, in biodegradable nanoparticles: Particle characteristics, in vitro cytotoxicity and evaluation of their body distribution. THE SPECIALIZED CONGRESS AND INTERNATIONAL EXHIBITION OF NANOMEDICINE, NANOBIOTECHNOLOGY, NANOBIOSENSORS AND NANOMATERIALS, 14-16 July 2009, Mashhad, Iran, Oral.

40-  Sayyed A. Sajadi Tabassi, Mohsen Tafaghodi_,  Nafiseh Amiri; PLGA nanospheres encapsulated with autoclaved Leishmania major (ALM) and CpG-ODN- Preparation and in vitro characterization. VACCINE 3^RD GLOBAL CONGRESS, 4-6 Oct 2009, Singapore, Poster 1.43.

41-  Eskandar Moghimipour , Seyyed Abolghassem Sajjadi Tabassi , Hadi Varghaei (2010) COMBINATION STRATEGIES FOR ENHANCING TRANSDERMAL ABSORPTION OF

THEOPHYLLINE THROUGH SHED SNAKE SKIN. Department  of  Pharmaceutics,  College  of  Pharmacy,  Jondishapour  University  of  Medical Sciences, Iran, and  Department of Pharmaceutics, College of Pharmacy, Mashhad University of Medical Sciences, Iran.

42-  Sayyed A. Sajadi TABASSI, P. EBRAHIMNEJAD, M.R. JAAFARI, F. ATYABI, R. DINARVAND (2010) Preparation and characterization of SN-38 nanoparticles using PLGA–PEG–Folate conjugates for folate-receptor-targeted anti-cancer therapy. International Conference on Cellular and Molecular Bioengineering, 2-4 Aug 2010, Singapore, Oral presentation.

43-  Sayyed A. Sajadi Tabassi, P. Ebrahimnejad, M.R. Jaafari, F. Atyabi, R. Dinarvand (2011) Preparation and Characterization of Poly Lactide-co-glycolide (PLGA) Nanoparticles encapsulated with SN-38. International Conference on Biomaterials Science 2011(ICBS2011). 15-18 March 2011, Tsukuba, Japan.

44-  Sayyed A. Sajadi Tabassi (2011) Cyclodextrin complexation and its applications in drug delivery. 5^th Iranian Controlled Release Conference, 12-14 March 2011, Mashhad, Iran.

45-  Sayyed Abolghasem Sajadi Tabassi, Elham Khodaverdi, Farzin Hadizadeh, Rahof Rashid. (2012) Preparation of hydrogels based on inclusion complexes of the triblock copolymer PCL-PEG-PCL with α-cyclodextrin (α-CD). 9^th International Gel Symposium (Gelsympo 2012), Tsukuba, Japan (oral presentation)

46-  Sayyed A Sajadi Tabassi, Seyed Ahmad Mohajeri, Seyedeh Vida Hashemi. (2012) Preparation of omeprazole imprinted polymer and study of its binding properties and drug release. 2^nd International Conference and Exhibition on Pharmaceutical, Nutraceutical and Cosmeceutical Technology (PharmaTech 2012), Kuala Lumpur, Malaysia. (oral presentation)

47-  Sayyed A Sajadi Tabassi (2012) Code of Professional Ethics in Pharmacy. 1^st International Conference on Pharmacoeconomy, 14-16 June 2012, Tehran, Iran, (oral presentation).

48-  Sayyed Abolghasem Sajadi Tabassi, Elham Khodaverdi, Farzin Hadizadeh, Rahof Rashid (2012)  Preparation of hydrogels based on inclusion complexes of the triblock copolymer PCL-PEG-PCL with α-cyclodextrin (α-CD), 13^th Iranian Pharmaceutical Science Congress, Isfahan, (oral presentation)

49-  J. Movaffagh, S.A. Sajadi Tabassi, A. Rastgoo (2012) Fabrication and characterization of controlled release system of theophylline in chitosan beads, 13^th Iranian Pharmaceutical Science Congress, Isfahan

                                                                    Honors & Awards

1-    Scholarship for PhD in the field of pharmaceutics from 1991-1995

2-    Premier Translator for translation of the book "Pharmaceutics" from English to Farsi (vol 1), Mashhad University of Medical Sciences, November 2006.

3-    Premier Translator for translation of the book "Pharmaceutics" from English to Farsi (vol 2), Mashhad University of Medical Sciences, November 2007.

4-    The translation of the book "Pharmaceutics" was chosen as the premier academic book by 2007 Research Festival of The University of Tehran, December 2007.

Members                                                  hip Membership

1- “Iranian Society of Pharmaceutical Scientists”, Tehran, Iran, 1995

2- “The Society of Iranian Pharmacists, Membership # 6657”, Tehran, Iran, 1998-present

3- “The Organization of Medical Order of Iran, Membership # D-2224”, Tehran, I.R. Iran, 1985-present

4- “UK Academy of Pharmaceutical Sciences”, Royal Pharmaceutical Society of Great Britain, London, UK, 1996-present

5- “International Pharmaceutical Federation, FIP, Membership # 24808”, The Netherlands, 2002-present

6- "The International Society of Oncology Pharmacy Practitioners" March 2006-present

                                                           Administrative Responsibilities

Jan 2008 – present; Professor of pharmaceutics, School of Pharmacy, Mashhad.

Jul 2003 – Jan 2008; Associate professor in pharmaceutics, School of Pharmacy, Mashhad.

Nov 1996 – Jul 2003, Assistant professor in pharmaceutics, School of Pharmacy, Mashhad.

Jun 1985 – Nov 1996, Lecturer in Pharmaceutics, School of Pharmacy, Mashhad.

2001-2003, Head of Department of Pharmaceutics, School of Pharmacy, Mashhad.

Jan 2006 – April 2008, Head of Department of Pharmaceutics, School of Pharmacy, Mashhad.

Aug 2005- present, Member of The Board of Examiners and Evaluation of Pharmaceutics of The Islamic Republic of Iran.

Feb 2013 – present, Head of Department of Clinical Traditional Medicine, School of traditional and Complimentary Medicine, Mashhad University of Medical Sciences (MUMS)

1998-2010 – Managing director and Head, 22Bahman Educational Pharmacy, School of Pharmacy, Mashhad

June 2015 – June 2016; Head, Department of Pharmaceutics, School of Pharmacy, Mashhad